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Video by Sgt. 1st Class Chantell Black

Guardian Response 25 - 76th ORC CRE Units

76th Operational Response Command

May 2, 2025 | 0:59

Army Reserve units assigned to the Chemical, Biological, Radiological, and Nuclear (CBRN) Response Enterprise (CRE) mission conducted validation training at Guardian Response 2025, which took place from April 25 - May 14, 2025. Guardian Response is a large-scale training exercise held yearly at the Muscatatuck Urban Training Center in Butlerville, IN, aimed at preparing U.S. Soldiers to respond to Chemical, Biological, Radiological and Nuclear (CBRN) threats and hazards within the United States. The exercise evaluates Soldier's Defense Support of Civilian Authorities (DSCA) response capabilities to ensure Soldier readiness as America's first line of defense.

The 87th Training Division, headquartered in Birmingham, Alabama, provides overall command and control of Guardian Response 2025. The division's mission is to train and validate Army Reserve units for combat and DSCA operations and ensure that participating organizations meet readiness and interoperability standards. The CRE units participating in Guardian Response 2025 included: 349th Chemical Company, Joint Base Lewis-McChord, Washington; 456th Medical Company Area Support, Somersworth, New Hampshire; and the 668th Engineer Vertical Construction Company, Orangeburg, New York. These units will stay on the CRE mission until 2027.